Your latest cannabis business info from Europe

Your latest cannabis business info from Europe

2023-04-05

What is the potential of CBD in Alzheimer’s disease treatment?

CBD and endocannabinoid system

The interaction of CBD with the endocannabinoid system is one of its primary modes of action. It is important in controlling a number of physiological functions, including mood, hunger, and pain perception. CBD modulates the cannabinoid receptor activation in the brain. This substance may have a protective impact against beta-amyloid-induced neurotoxicity. Thus, CBD can be helpful in Alzheimer’s disease treatment.

CBD and Alzheimer’s disease

CBD may have antioxidant and anti-inflammatory characteristics that could be helpful for Alzheimer’s disease in addition to its effects on the endocannabinoid system. Based on a study released in the “Clinical Therapeutics” journal, by modifying the activity of certain receptors in the brain, CBD may have a potential function in the treatment of Alzheimer’s disease. Alzheimer’s disease proves to be highly affected by chronic inflammation. Numerous preclinical and clinical research on CBD have demonstrated that it has anti-inflammatory properties.

A female mouse model of Alzheimer’s disease was in a research to look at how long-term cannabidiol (CBD) treatment affects learning and anxiety (AD).

The study used female mice that had been bred to exhibit symptoms similar to those of AD. Starting when the mice were 2 months old, they received CBD treatments for 8 months, or a control solution. The mice went through a series of behavioral tests to assess their cognitive abilities and anxiety-like behavior.

In comparison to the control group, the CBD-treated mice had less anxiety-like behavior and improved cognitive function. Also, we can see that the CBD therapy decreased inflammation in the brain, another characteristic of Alzheimer’s disease. According to the scientists, long-term CBD use may have therapeutic benefits for Alzheimer’s by improving cognitive function and lowering anxiety-like behavior, possibly due to its anti-inflammatory properties.

What is the potential of CBD as a treatment?

Overall, these results show that CBD may have a promising function in the treatment of this severe neurodegenerative ailment. Even if only further research can help to fully understand the potential therapeutic effects of CBD on Alzheimer’s disease. To completely comprehend the therapeutic potential of CBD for AD more research is necessary. Also to determine the ideal dosage and course of treatment. The most recent in vitro and in vivo results support future research. Only a few clinical trials have been conducted as of yet. Accordingly, more study will assess the efficacy of cannabinoid-based medications for treating AD, as well as their safety, pharmacokinetic, pharmacodynamic, and most importantly, their safety.

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